Benign Prostatic Hyperplasia (BPH)

Overview

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Benign Prostatic Hyperplasia (BPH) is a common condition in older men where the prostate gland becomes enlarged, leading to urinary symptoms. Unlike prostate cancer, BPH is non-cancerous and involves the proliferation of prostate tissue, which can obstruct the flow of urine.

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Symptoms

Symptoms of BPH are Primarily related to Urinary Function and can vary in Severity. Common Symptoms include

  • Frequent Urination: Needing to urinate more often than usual, especially at night (nocturia).
  • Urgency: A sudden, strong need to urinate.
  • Weak Urine Stream: A reduced or intermittent flow of urine.
  • Difficulty Starting Urination: Struggling to begin urinating despite feeling the need.
  • Incomplete Bladder Emptying: Feeling that the bladder is not completely emptied after urination.
  • Straining: The need to push or strain to start or finish urinating.
  • Dribbling: Leakage of urine after finishing urination.
Complications

If left Untreated, BPH can Lead to Several Complications, including

  • Urinary Tract Infections (UTIs): Caused by stagnant urine in the bladder.
  • Bladder Stones: Formed from minerals in the stagnant urine.
  • Bladder Damage: Chronic urinary retention can stretch and damage the bladder.
  • Kidney Damage: Severe obstruction can lead to backflow of urine into the kidneys (hydronephrosis) and potentially cause kidney damage.
  • Acute Urinary Retention: Sudden inability to urinate, which can be painful and requires immediate medical attention.
Causes

The Exact cause of BPH is not fully understood, but Several Factors are Believed to Contribute

  • Aging: The risk of BPH increases with age, often affecting men over 50.
  • Hormonal Changes: Imbalances in sex hormones, such as testosterone and estrogen, may play a role.
  • Genetics: A family history of BPH or prostate problems may increase the risk.
Prevention

While BPH cannot be Entirely Prevented, Certain Lifestyle changes and Practices may help Reduce the Risk or Alleviate symptoms

  • Healthy Diet: A diet rich in fruits, vegetables, and healthy fats might be beneficial.
  • Regular Exercise: Engaging in regular physical activity can support overall health and potentially reduce the risk of BPH.
  • Healthy Weight: Maintaining a healthy weight may help reduce the risk of prostate enlargement.
Risk Factors

Risk Factors for Developing BPH include

  • Age: BPH is more common in older men, particularly those over 50.
  • Family History: Having a family history of BPH or prostate problems increases risk.
  • Hormonal Factors: Imbalances in sex hormones due to aging or other factors may contribute.
  • Lifestyle Factors: Diet, obesity, and physical inactivity may influence the risk.
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How is it treated?

Treatment of BPH

Treatment options for BPH depend on the severity of symptoms and complications

  • Lifestyle Modifications: For mild symptoms, changes such as reducing fluid intake before bedtime, avoiding caffeine and alcohol, and regular exercise can help manage symptoms.

Medications

  • Alpha-Blockers: These medications, such as tamsulosin, help relax the muscles around the prostate and bladder neck to ease urine flow.
  • 5-Alpha-Reductase Inhibitors: Medications like finasteride and dutasteride can shrink the prostate over time by blocking hormones that contribute to prostate growth.
  • Combination Therapy: Sometimes, a combination of alpha-blockers and 5-alpha-reductase inhibitors is used for more effective symptom relief.

Minimally Invasive Procedures

  • Transurethral Resection Of The Prostate (TURP): A surgical procedure that removes part of the prostate through the urethra.
  • Laser Therapy: Uses laser energy to remove or destroy prostate tissue.
  • Urolift: A procedure that uses implants to lift and hold the enlarged prostate tissue out of the way.

Surgery

  • Open Prostatectomy: A more invasive procedure for very large prostates or when other treatments are not effective.
  • Regular Monitoring: For mild cases, regular check-ups and monitoring may be sufficient.
  • Early diagnosis and treatment of BPH can help manage symptoms effectively and prevent complications. If symptoms are affecting quality of life or causing significant problems, consulting a healthcare provider is important for appropriate evaluation and management.
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How is it Diagnosed?

Benign Prostatic Hyperplasia (BPH) is diagnosed through a combination of clinical assessment, symptom scoring, physical examination, and diagnostic tests. The diagnostic process begins with a detailed medical history focusing on lower urinary tract symptoms (LUTS) such as frequency, urgency, nocturia, weak stream, or incomplete bladder emptying.

The International Prostate Symptom Score (IPSS) questionnaire is commonly used to assess symptom severity and impact on quality of life.

A digital rectal examination (DRE) allows the physician to evaluate prostate size and consistency. A smooth, enlarged, non-tender prostate typically indicates BPH, whereas hard or irregular findings may suggest malignancy.

Urinalysis is done to exclude urinary tract infection or hematuria. Serum ProstateSpecific Antigen (PSA) levels may be tested to screen for prostate cancer, although elevated PSA can also occur in BPH.

Ultrasound, particularly transrectal ultrasound (TRUS), can provide detailed prostate volume measurements. Post-void residual (PVR) urine measurement is done via ultrasound to evaluate bladder emptying efficiency.

In selected cases, urodynamic studies are used to assess bladder function. Cystoscopy may be performed to visualize the urethra and bladder, especially when hematuria or recurrent infections are present.

These assessments help confirm the diagnosis of BPH, rule out other causes like prostate cancer or bladder stones, and guide treatment options, which may include medication or surgical intervention based on symptom severity and patient preference.

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