Asthma

Overview

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Asthma is a chronic respiratory condition characterized by inflammation and narrowing of the airways, leading to difficulty breathing. It can vary in severity and often leads to episodes of wheezing, breathlessness, and coughing. Asthma can be managed effectively with appropriate treatment and lifestyle adjustments, but it is a long-term condition that requires ongoing management.

It can vary in severity and often leads to episodes of wheezing, breathlessness, and coughing. Asthma can be managed effectively with appropriate treatment and lifestyle adjustments, but it is a long-term condition that requires ongoing management.

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Symptoms
  • Wheezing: A high-pitched whistling sound during breathing, particularly during exhalation.
  • Shortness of Breath: Difficulty breathing, especially during physical activity or at night.
  • Coughing: Persistent cough, which may be worse at night or early in the morning.
  • Chest Tightness: Feeling of pressure or tightness in the chest.
  • Increased Mucus Production: Thick mucus or phlegm that may be difficult to clear from the airways.
Complications
  • Severe Asthma Attacks: Life-threatening episodes where the airways become severely constricted, requiring emergency treatment.
  • Chronic Airway Remodeling: Long-term inflammation can lead to structural changes in the airways, potentially affecting lung function.
  • Frequent Respiratory Infections: Increased risk of infections such as pneumonia or bronchitis due to compromised airway function.
  • Reduced Quality of Life: Persistent symptoms can impact daily activities, sleep, and overall well-being.
Causes
  • Allergens: Exposure to substances such as pollen, dust mites, mold, pet dander, and cockroach droppings can trigger asthma symptoms.
  • Irritants: Tobacco smoke, air pollution, strong odors, and chemical fumes can exacerbate asthma.
  • Respiratory Infections: Viral infections, especially in early childhood, can increase the risk of developing asthma or trigger asthma exacerbations.
  • Exercise: Physical activity, particularly in cold or dry air, can trigger asthma symptoms in some individuals.
  • Weather Changes: Extreme weather conditions, such as cold air or high humidity, can worsen asthma symptoms.
  • Emotional Stress: Stress and strong emotions can trigger or worsen asthma symptoms.
Prevention
  • Avoid Triggers: Identify and avoid known allergens or irritants that trigger asthma symptoms.
  • Medication Adherence: Use prescribed asthma medications regularly as directed to maintain control over symptoms.
  • Allergy Management: Manage allergies with avoidance strategies and medications as advised by a healthcare provider.
  • Regular Monitoring: Monitor symptoms and peak flow measurements to detect worsening of asthma and adjust treatment as needed.
  • Healthy Lifestyle: Maintain a healthy diet, exercise regularly, and manage stress to support overall health and potentially reduce asthma symptoms.
  • Vaccinations: Stay up-to-date with vaccinations, such as the flu vaccine, to prevent respiratory infections that can exacerbate asthma.
Risk Factors
  • Family History: Having a family history of asthma or other allergic conditions increases the risk.
  • Personal History: Previous respiratory conditions, such as childhood wheezing or respiratory infections, can increase the likelihood of developing asthma.
  • Environmental Factors: Exposure to tobacco smoke, pollution, or allergens during early childhood can contribute to asthma development.
  • Occupation: Certain jobs with exposure to irritants or allergens can increase the risk of occupational asthma.
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How is it Treated?

Medications:

  • Inhaled Corticosteroids: The mainstay of long-term asthma control to reduce inflammation in the airways (e.g., fluticasone, budesonide).
  • Long-Acting Beta Agonists (LABAs): Used in combination with inhaled corticosteroids for better control of asthma symptoms (e.g., salmeterol, formoterol).
  • Leukotriene Receptor Antagonists: Oral medications that help reduce inflammation and bronchoconstriction (e.g., montelukast).
  • Short-Acting Beta Agonists (SABAs): Rescue inhalers used for quick relief of acute symptoms (e.g., albuterol, levalbuterol).
  • Theophylline: An oral medication that helps relax the airways and improve breathing.

Allergy Treatments:

  • Allergen Immunotherapy: Allergy shots or sublingual tablets that may help reduce sensitivity to specific allergens.
  • Anti-IgE Therapy: Monoclonal antibodies (e.g., omalizumab) used for severe allergic asthma to reduce allergic responses.

Lifestyle and Home Management:

  • Asthma Action Plan: Develop a personalized plan with a healthcare provider to manage symptoms, use medications, and recognize when to seek medical help.
  • Peak Flow Monitoring: Regular use of a peak flow meter to track airway function and detect early signs of worsening asthma.

Emergency Care:

  • Quick-Relief Medications: Use of rescue inhalers during an asthma attack to quickly open the airways.
  • Emergency Medical Attention: Seek immediate help if symptoms do not improve with medication, or if there is severe shortness of breath or difficulty breathing.
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How is it Diagnosed?

Asthma is a chronic inflammatory disease of the airways characterized by variable airflow obstruction and bronchial hyperresponsiveness. Diagnosis involves clinical assessment and pulmonary function tests.

History is central to diagnosis. Symptoms typically include wheezing, shortness of breath, chest tightness, and cough—often worse at night or early morning and triggered by allergens, exercise, cold air, or infections. A personal or family history of atopy (eczema, allergic rhinitis) supports the diagnosis.

Physical examination during an acute episode may reveal wheezing, prolonged expiration, and use of accessory muscles. However, between episodes, examination can be normal.

Spirometry is the main diagnostic test. It measures forced expiratory volume in one second (FEV₁) and forced vital capacity (FVC). A reduced FEV₁/FVC ratio that improves significantly (>12% and >200 mL increase in FEV₁) after bronchodilator inhalation confirms reversible airway obstruction.

Peak expiratory flow rate (PEFR) monitoring can help track variability in airway obstruction. In children or those unable to perform spirometry, clinical diagnosis with symptom pattern and treatment response may guide diagnosis.

    Additional tests include:

  • Allergy testing (skin prick or IgE)
  • Exhaled nitric oxide (FeNO) – marker of airway inflammation
  • Chest X-ray – to exclude other conditions
  • Asthma diagnosis is clinical but reinforced by objective tests. Accurate diagnosis
  • ensures appropriate therapy with inhaled corticosteroids and bronchodilators to control symptoms and prevent exacerbations.

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FAQs

  • Asthma is a chronic respiratory condition that causes inflammation and narrowing of the airways, leading to difficulty breathing.

Symptoms may include:

  • Wheezing
  • Shortness of breath
  • Chest tightness
  • Coughing (especially at night or early morning)

  • Common triggers include allergens (like pollen, dust mites, and pet dander), smoke, exercise, cold air, and respiratory infections.

  • Diagnosis typically involves a medical history review, physical examination, and lung function tests (spirometry).

Treatment options include:

  • Inhaled corticosteroids
  • Bronchodilators
  • Leukotriene modifiers
  • Lifestyle changes (avoiding triggers)
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Website Design and Development by Sterco Digitex

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