Alopecia

Overview

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Alopecia refers to hair loss that can occur on the scalp or other parts of the body. It can affect people of all ages, genders, and ethnicities, and its severity can vary. Alopecia may be temporary or permanent, depending on the cause and type.

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Symptoms
  • Hair Thinning: Gradual thinning on the top of the head is the most common form.
  • Sudden Hair Loss: Large clumps of hair may fall out suddenly.
  • Bald Patches: Circular or patchy bald spots can appear on the scalp or other areas.
  • Hair Loss over the Body: Hair may fall from the entire body, including eyebrows, eyelashes, and beard.
  • Scaly Patches: Associated with conditions like tinea capitis (scalp ringworm).
  • Broken Hairs: Common in some types of alopecia, like alopecia areata.
Complications
  • Emotional distress: Hair loss can affect self-esteem, causing anxiety or depression.
  • Sunburn: Loss of scalp hair increases the risk of sunburn on the scalp.
  • Infection: In some cases, bald patches may become infected, particularly if skin lesions or irritation occur.
  • Permanent Hair Loss: Some types, like scarring alopecia, may lead to irreversible hair loss.
Causes
  • Genetic Factors: Hereditary hair loss, such as androgenic alopecia (male and female pattern baldness).
  • Autoimmune Disease: Alopecia areata occurs when the immune system attacks hair follicles.
  • Hormonal Changes: Pregnancy, menopause, thyroid issues, and conditions like PCOS.
  • Medications: Chemotherapy, radiation, and drugs for arthritis, depression, and heart disease.
  • Stress and Trauma: Physical or emotional stress can lead to telogen effluvium, a type of hair loss.
  • Infections: Fungal infections like ringworm can cause hair loss.
  • Nutritional Deficiencies: Lack of nutrients such as iron, vitamin D, or protein.
  • Hairstyling Practices: Tight hairstyles or treatments like perming can lead to traction alopecia.
Prevention
  • Gentle Hair Care: Avoid tight hairstyles, harsh chemicals, and excessive heat styling.
  • Healthy Diet: Eat a balanced diet rich in essential nutrients like iron, vitamin D, and biotin.
  • Manage Stress: Practice stress-reducing techniques, such as meditation or exercise.
  • Medical Checkups: Regular screenings for conditions like thyroid disease or lupus.
  • Avoid Triggers: Limit exposure to chemicals or habits that damage hair, like smoking.
Risk Factors
  • Family History: A family history of alopecia or autoimmune diseases can increase the risk.
  • Age: Hair loss often begins in middle age but can start earlier.
  • Sex: Men are more likely to experience male-pattern baldness.
  • Chronic Illnesses: Conditions such as lupus, diabetes, or thyroid problems.
  • Medications: Drugs that impact hormonal balance or immune function.
  • Stress: Both physical and emotional stress can trigger hair loss.
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How is it Treated?

Medications

  • Minoxidil (Rogaine): Over-the-counter topical treatment that promotes hair regrowth.
  • Finasteride (Propecia): Prescription medication used to treat male-pattern baldness.
  • Corticosteroids: Injected or topical steroids can reduce inflammation in autoimmune forms like alopecia areata.
  • Anthralin: A topical medication that may promote hair regrowth in alopecia areata.
  • JAK inhibitors: Recently developed oral or topical drugs targeting the immune response in alopecia areata.
  • Hair Transplant: Surgical treatment where hair follicles are moved from one part of the body to thinning or balding areas.
  • PRP Therapy: Platelet-rich plasma (PRP) injections may stimulate hair growth by enhancing follicle function.
  • Laser Therapy: Low-level laser therapy (LLLT) uses red light to stimulate hair follicles.
  • Wigs or Hairpieces: Non-surgical options for those with extensive hair loss."
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How is it Diagnosed?

Alopecia, or hair loss, is diagnosed through clinical examination and a detailed medical history. The physician evaluates the pattern, extent, and duration of hair loss and asks about family history, recent illnesses, medications, or stress, which may contribute.

The type of alopecia—such as alopecia areata, androgenetic alopecia, or telogen effluvium—is usually distinguished based on clinical features. Scalp examination helps identify signs like broken hairs, exclamation point hairs, inflammation, or scarring.

A hair pull test may be performed to assess active hair shedding. The test involves gently pulling a small section of hair to see how many strands come out. A trichoscopy (dermatoscopic examination of the scalp) provides a magnified view of hair follicles and shaft abnormalities.

For further clarification, a scalp biopsy may be done. A small piece of scalp tissue is removed and examined microscopically to detect autoimmune activity, inflammation, or scarring.

Blood tests are frequently ordered to rule out underlying causes such as thyroid dysfunction (TSH), iron deficiency (serum ferritin), vitamin D or B12 deficiency, and autoimmune disorders (ANA test).

Diagnosis is tailored based on the suspected type and cause of alopecia. Identifying reversible factors early is crucial for effective management and prognosis.

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FAQs

While some forms of alopecia are reversible, such as telogen effluvium, others like androgenic alopecia may only be managed with treatments to slow hair loss or stimulate regrowth.

The speed varies; in cases like alopecia areata, hair loss can be sudden and rapid, while androgenic alopecia progresses more gradually.

Yes, Hereditary factors play a role, especially in androgenic alopecia (pattern baldness).

In severe cases, such as alopecia universalis, all body hair can be lost, including on the scalp, face, and other areas.

No, it can affect any part of the body where hair grows, including eyebrows, eyelashes, and beards.

Generally, alopecia itself is not painful, though some people may experience scalp sensitivity or itching before hair loss.

Nutritional deficiencies, such as iron or vitamin D deficiencies, can contribute to hair loss.

No, alopecia is not contagious, though hair loss caused by infections like ringworm can spread between individuals.

Maintaining a healthy diet, avoiding stress, and practicing good hair care can help, but medical treatment may be necessary for significant hair loss.

A dermatologist may diagnose alopecia through a scalp exam, biopsy, blood tests, and reviewing medical history.

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