Acute Appendicitis

Overview

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Acute appendicitis is a medical condition where the appendix, a small tube-shaped pouch attached to the large intestine, becomes inflamed and infected. It is a common emergency condition that often requires surgical intervention.

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Symptoms

The Symptoms of Acute Appendicitis can vary but typically include:

  • Abdominal Pain: Often starting around the belly button and shifting to the lower right side of the abdomen.
  • Nausea and Vomiting: Often following the onset of pain.
  • Loss of Appetite: A noticeable decrease in hunger.
  • Fever: Mild to moderate fever can be present.
  • Constipation or Diarrhea: Changes in bowel habits can occur.
  • Abdominal Swelling: In some cases, the abdomen may become swollen or tender.
Complications

If Left Untreated, Acute Appendicitis can Lead to Serious Complications, such as:

  • Perforation: A burst appendix can spread infection into the abdominal cavity, leading to peritonitis, a severe and widespread abdominal infection.
  • Abscess Formation: A collection of pus that forms in the abdomen.
  • Sepsis: A life-threatening systemic infection that can result from the spread of infection.
  • Bowel Obstruction: Scarring or infection can cause a blockage in the intestines
Causes

The Exact cause of Acute Appendicitis is not always clear, But it is Often Attributed to:

  • Obstruction: Blockage of the appendix, often by stool, a foreign body, or cancer.
  • Infection: An infection in the digestive tract that leads to inflammation.
  • Genetic Factors: There may be a hereditary component, although this is less well understood.
Prevention

Several Factors can increase the Likelihood of Developing Acute Appendicitis:

  • Age: Most commonly affects individuals between the ages of 10 and 30.
  • Gender: Slightly more common in males than females.
  • Family History: A family history of appendicitis can increase risk.
  • Diet: Low fiber diets have been associated with an increased risk.
  • Infections: Previous gastrointestinal infections might increase the risk.
Risk Factors

While Acute Appendicitis cannot always be Prevented, Certain Practices may Reduce the Risk:

  • Diet: Consuming a diet high in fiber may help prevent appendicitis.
  • Regular Check-ups: Prompt treatment of gastrointestinal infections may reduce risk.
  • Healthy Lifestyle: Maintaining overall health and hygiene can contribute to reducing the risk
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How is it treated?

Treatment for acute appendicitis typically involves:

  • Surgical Removal: The primary treatment is an appendectomy, a surgical procedure to remove the inflamed appendix. This can be done through open surgery or laparoscopically.
  • Antibiotics: Administered before, during, and after surgery to treat and prevent infection.
  • Pain Management: Medications to control pain and discomfort.
  • Postoperative Care: Includes recovery instructions and follow-up visits to ensure proper healing.
  • In cases where surgery is not immediately possible or if there are other health complications, treatment may involve antibiotics and careful monitoring until surgery can be performed.
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How is it Diagnosed?

Acute appendicitis is a common surgical emergency caused by inflammation of the appendix, typically due to obstruction. The diagnosis starts with a focused clinical history—periumbilical pain that migrates to the right lower quadrant (RLQ), nausea, vomiting, anorexia, and low-grade fever.

Physical examination reveals RLQ tenderness, especially at McBurney’s point. Classical signs include Rovsing's, Psoas, and Obturator signs, which suggest peritoneal irritation. Rebound tenderness and guarding are also common.

Initial laboratory tests show elevated white blood cell count (WBC) with neutrophilia. Creactive protein (CRP) may also be elevated, supporting the inflammatory process.

Imaging studies play a critical role in confirming the diagnosis. Ultrasound is preferred in children and pregnant women, showing a non-compressible, dilated appendix. In adults, CT scan of the abdomen and pelvis with contrast is the most accurate, demonstrating a dilated appendix (>6 mm), wall thickening, peri-appendiceal fat stranding, or abscess formation.

In equivocal cases, diagnostic laparoscopy may be both diagnostic and therapeutic. Prompt diagnosis is crucial, as delayed treatment increases the risk of perforation and peritonitis. Hence, appendicitis is often a clinical diagnosis supported by imaging and labs.

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